Design of low density SNP chips for genotype imputation in layer chicken
نویسندگان
چکیده
منابع مشابه
Design of a Bovine Low-Density SNP Array Optimized for Imputation
The Illumina BovineLD BeadChip was designed to support imputation to higher density genotypes in dairy and beef breeds by including single-nucleotide polymorphisms (SNPs) that had a high minor allele frequency as well as uniform spacing across the genome except at the ends of the chromosome where densities were increased. The chip also includes SNPs on the Y chromosome and mitochondrial DNA loc...
متن کاملPosters IMPUTATION OF MISSING GENOTYPES IN HIGH DENSITY SNP DATA
The accuracy and computational complexity of five methods to impute missing genotypes in high density SNP data was investigated. The haplotype reconstruction package fastPHASE reached the highest accuracies (91% to 98%) for varying proportions (0.2% to 8%) of missing genotypes. Alternative methods based on principal component analysis were less accurate (67% to 94%), but their computational dem...
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Genotype imputation from low-density to high-density (SNP) chips is an important step before applying genomic selection, because denser chips can provide more reliable genomic predictions. In the current research, the accuracy of genotype imputation from low and moderate-density panels (5K and 50K) to high-density panels in the purebred and crossbred populations was assessed. The simulated popu...
متن کاملEvaluation of developed low-density genotype panels for imputation to higher density in independent dairy and beef cattle populations.
The objective of this study was to develop, using alternative algorithms, low-density SNP genotyping panels (384 to 12,000 SNP), which can be accurately imputed to higher-density panels across independent cattle populations. Single nucleotide polymorphisms were selected based on genomic characteristics (i.e., linkage disequilibrium [LD], minor allele frequency [MAF], and genomic distance) in a ...
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برای پردازش سیگنال آنالوگ در شبکه های عصبی ، معمولا نیاز به یک واحد حافظه آنالوگ احساس میشود که بدون احتیاج به a/d وd/a بتواند بطور قابل انعطاف و مطمئن اطلاعات آنالوگ را در خود ذخیره کند. این واحد حافظه باید دارای دقت کافی ، سرعت بالا ، توان تلفاتی کم و سایز کوچک باشد و همچنین اطلاعات را برای زمان کافی در خود نگهدارد. برای پیاده سازی سیستمی که همه این قابلیتها را در خود داشته باشد، کوشش...
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ژورنال
عنوان ژورنال: BMC Genetics
سال: 2018
ISSN: 1471-2156
DOI: 10.1186/s12863-018-0695-7